Beyond Gap Junction Channel Function: the Expression of Cx43 Contributes to Aldosterone-Induced Mesangial Cell Proliferation via the ERK1/2 and PKC Pathways
Aims: This study aimed to explore the precise mechanism and signaling pathways of mesangial cell (MC) proliferation from a new point of view considering Connexin 43 (Cx43).Methods: MC proliferation was measured by the incorporation of 3H-thymidine (3H-TdR).Cx43 was over-expressed in MC cells using lipofectamine 2000, and the expression level Differ